Knowledge

September 20, 2023

Viral vector manufacturing: Production methods & future advances

Khalil Essani - Single Use Support
Khalil Essani

Viral vector manufacturing involves advanced biotechnological methods, with scalability being one of the major difficulties. In this article, we will discuss both challenges and innovative approaches for viral vector production.

September 20, 2023

Viral vector vaccines vs. mRNA vaccines: The differences

michael-muehlegger
Michael Mühlegger

There are several differences, but also a few significant similarities between viral vector vaccines and non-viral-vector based mRNA vaccines – we will uncover them in this article.

September 20, 2023

Viral vector simply explained

michael-muehlegger
Michael Mühlegger

Viral vectors have become an indispensable tools in therapeutic and research applications. In this article, we will provide a broad overview of this fascinating topic.

September 20, 2023

Aliquotation & homogenization of viral vectors

BRMO
Brian Moloney

In this article, we uncover the significance of a professional aliquotation process, the challenges entailed in filling viral vectors like AAVs, and the innovative solutions supporting to master those challenges.

September 20, 2023

Freezing & thawing viral vectors: Best practices

Alexander Fuchs | Single Use Support
Alexander Fuchs

Proper handling of viral vectors during storage, freezing, and thawing is crucial to maintaining their integrity and efficacy. In this article, we will explore best practices for preserving viral vectors, ensuring their stability, and maximizing their potential for various applications.

September 20, 2023

Safe storage & handling of viral vectors

Claus Exenberger - Single Use Support
Claus Exenberger

Viral vectors like Adeno-associated viruses (AAVs) are popular vectors for gene therapy and vaccines. And yet, there is product loss due to leakages of primary packagings or other mishandling of fluids. In order to deliver high-quality and viable products efficiently, safe handling experience a growing interest.

September 19, 2023

3 Examples of FDA approved AAVs in gene therapy

michael-muehlegger
Michael Mühlegger

In this blog post, we'll show examples of AAVs as gene therapy vectors and examine the tangible results of FDA-approved AAV gene therapies, which offer actual solutions and hope for patients affected by genetic disorders. 

September 19, 2023

What is the difference between adeno-associated virus and adenovirus?

michael-muehlegger
Michael Mühlegger

The main difference between adeno-associated viral vectors (AAV) and adenoviral vectors (AVV) is their genetic makeup. AAV is composed of a single-stranded DNA viral vector, while adenoviral vectors consist of double-stranded DNA.

September 19, 2023

Types of viral vectors

michael-muehlegger
Michael Mühlegger

Various types of viral vectors are central to genetic research and medical advancements. These small carriers, obtained from various viruses, play an essential role in gene therapy and beyond. In this exploration, we will examine different types, the applications, unique attributes, and the complex terrain of producing viral vectors.

September 18, 2023

Adeno-Associated Virus (AAV) for gene therapy

Khalil Essani - Single Use Support
Khalil Essani

The adeno-associated virus (AAV) is a very popular viral vector with great potential available for gene delivery. This article explores AAV vectors, their role in gene therapy, and their associated advantages and disadvantages.

September 13, 2023

Plasmid DNA manufacturing companies – market overview

daniel-tischler
Daniel Tischler

In this article, we will give an overview of the pDNA manufacturing market – not only taking a look at the dry figures, but also highlighting the services that are offered by important plasmid DNA manufacturing companies.

September 13, 2023

What is the function of plasmid DNA?

michael-muehlegger
Michael Mühlegger

Plasmid DNA fulfills several functions in bacteria, but they are also widely used in the biopharma sector. In this article, we will uncover their key functions.