Knowledge
August 3, 2023
Types of cell banks: An overview
In cell banking, one can distinguish four different types of cell banks, all of which are involved in the manufacturing of cell-based products. In this article, we will discuss them all.
August 3, 2023
Cell bank manufacturing: From master to working cell bank
Cell banks are fundamental in the production of several biopharmaceutical products, their manufacturing a highly complex process. In this article, we will explain cell bank manufacturing in detail, including the challenges it is related to.
August 2, 2023
The differences between master cell bank (MCB) and working cell bank (WCB)
Both master and working cell banks belong to the four general types of cell banks. Although having much in common, there are some major differences between MCBs and WCBs, which we will uncover in this article.
August 2, 2023
Cryopreservation of cells: Preserving cells for future use
Cryopreservation is a necessary procedure to maintain cell viability during ex vivo storage. In this article, we will provide some general information on cell cryopreservation, but also discuss different tools, challenges and an exemplary protocol.
August 1, 2023
How to maintain a cell bank?
Proper storage of cells and maintenance of a cell bank is essential to uphold the integrity and reproducibility of experimental results. In this article, we will show best practices for maintaining a cell bank, from initial cell line characterization to cGMP compliance, storage, and troubleshooting tips.
August 1, 2023
Advantages of cell banking
By preserving and storing valuable cell lines, cell banking ensures a stable and consistent source of cells for various applications. In this blog post, we will explore the numerous advantages of cell banking and its pivotal role in driving advancements in the fields of science and medicine.
August 1, 2023
The purpose of cell banking: Uses & Applications
At the core of cutting-edge research and biopharmaceutical production lies the crucial need to preserve and store precious cell lines, ensuring their availability for future studies and therapeutic applications. In this article, we will explore the purpose and applications of cell banking, examining its significance in scientific discoveries and medical breakthroughs.
August 1, 2023
Cell banking: Definition, Process & Manufacturing
Cell banking plays a key role in securing valuable cell lines and biological resources for future research and applications in the field of biotechnology. This article aims to provide a comprehensive overview of cell banking, its definition, importance, and the essential components involved in establishing and maintaining cell banks.
August 1, 2023
Freezing cells – considerations and solutions
A fundamental process to preserve the ex vivo viability of cells is freezing them to extremely low temperatures. This is a complex and delicate task, requiring both expertise and professional equipment. In this article, we will take a look at the most important aspects of the cell freezing process.
July 31, 2023
How to measure and improve cell viability?
Cell viability is a fundamental parameter in cell-based biopharma processing and cell banking. Therefore, it is essential not only to measure cell viability, but also to take measures for its improvement. Learn more in this article.
July 28, 2023
Cryovessels in Biopharmaceutical Manufacture: When Does the Tank Run Out?
It is many decades since cryovessels emerged as a groundbreaking solution in the biopharmaceutical industry, enabling the safe and efficient storage of bulk drug substances. However, the introduction of plate-based freezing methods has further advanced the technology available for the freezing of biopharmaceuticals, offering improved product quality and consistency.
July 28, 2023
Lyophilization considerations: Comparing freeze-drying to freezing for biopharmaceutical products
Not all biopharmaceuticals are suitable for freeze-drying. Depending on the specific stability requirements the preservation of biopharmaceuticals is either with cryopreservation or lyophilization.